EFFECT OF INDOMETHACIN ON GALVANIC CORROSION OF COPPER AND STAINLESS STEEL ON INTRAUTERINE DEVICE

J Chin Soc Corr Pro

1998, Vol. 18

Issue (2): 81-86 DOI:

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EFFECT OF INDOMETHACIN ON GALVANIC CORROSION OF COPPER AND STAINLESS STEEL ON INTRAUTERINE DEVICE

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Abstract

7 -type active intrauterine device (IUD) is made of pure copper and stainless steel together with indomethacin for blood loss control. Galvanic corrosion behavior of the two dissimilar metals in the absence and presence of indomethacin were compared in physiological saline with pH 6-8. Indomethacin did not affect corrosion potential of copper, but caused stainless steel a slight potential shift towards positive. With increasing pH of the media, copper potential shifted towards positive, whereas stainless steel potential shifted towards negative. Indomethacin did not change these dependence. In the copper/stainless steel couple, copper acted as anode. Anodic polarization behaviour of copper was not altered by indomethacin, but its cathodic polarization curve was moved up. Indomethacin increased the galvanic current significantly. It was also noticed that stainless steel might be activated due to improper handling of the IUD. In this case, copper became cathode of the couple and its corrosion would be suppressed. Indomethacin did not turn the stainless steel from active state into passive state.

Key words: Galvanic corrosion Copper Stainless steel Indomethacin Intrauterine device

Received: 25 April 1998

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XUE Hua-shi XU Nai-xin ZHANG Cheng-dian CHEN Yue-zhen SHEN Yi-yun (Shanghai Institute of Metallurgy; Chinese Academy of Sciences; Shanghai 200050) (Shanghai Institute of Planned Parenthood Research)(Shanghai Medical Suture Needle Factory). EFFECT OF INDOMETHACIN ON GALVANIC CORROSION OF COPPER AND STAINLESS STEEL ON INTRAUTERINE DEVICE. J Chin Soc Corr Pro, 1998, 18(2): 81-86.

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https://www.jcscp.org/EN/ OR https://www.jcscp.org/EN/Y1998/V18/I2/81

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