The superamphiphobic surface was prepared on B10 Cu-alloy by etching with (NH₄)₂S₂O₈ and NaOH mixed solution, followed by oxidation at 160 ℃ and fluorosilane modification. The microscopic morphology, chemical composition and electrochemical property of the superamphiphobic surface were characterized by means of Laser scanning confocal microscopy (LSCM), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and electrochemical means etc.Results show that the optimal preparation conditions were etching at 40 ℃ for 5 h, oxidation at 160 ℃ for 1 h, and 1.0% fluorosilane modification for 1 h. The superamphiphobic surface presents contact angle of water and ethylene glycol 158.1° and 151.2° and the rolling angle close to 0° and 5°, respectively. The electrochemical test shows that compared with the bare alloy, the free corrosion potential of the superamphiphobic alloy is shifted to -0.204 V versus calomel electrode used as the reference electrode, the corrosion current density decreases from 1.192 × 10^-5 A·cm^-2 to 1.649 × 10^-6 A·cm^-2, the corrosion suppression efficiency is 94.3%, and the corrosion resistance is significantly improved. Self-cleaning performance test indicates that the superamphiphobic surface possess excellent self-cleaning properties, and mechanical wear resistance test shows that the superamphiphobic surface can maintain a certain protective effect on the substrate over a long sliding distance.